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1.14.19.55: 4-hydroxybenzoate brominase (decarboxylating)

This is an abbreviated version!
For detailed information about 4-hydroxybenzoate brominase (decarboxylating), go to the full flat file.

Reaction

3,4-dihydroxybenzoate
+ 2 NADPH + 2 bromide + 2 O2 + 2 H+ =
3,5-dibromobenzene-1,2-diol
+ 2 NADP+ +
CO2
+ 4 H2O

Synonyms

bmp5

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)

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Resultsin table
2Cloned(Commentary)
2Cofactor
4General Information
6Organism
1Pathway
6Reaction
4Reference
16Substrates and Products (Substrate)
3Synonyms
1Systematic Name

Substrates Products

Substrates Products on EC 1.14.19.55 - 4-hydroxybenzoate brominase (decarboxylating)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2,4-dihydroxybenzoate + 2 NADPH + 2 bromide + 2 O2 + 2 H+
2,4-dibromo-6-hydroxyphenol + 4-bromo-2-hydroxyphenol + 2 NADP+ + CO2 + 4 H2O
show the reaction diagram
3,4-dihydroxybenzoate + 2 NADPH + 2 bromide + 2 O2 + 2 H+
2,4-dibromo-6-hydroxyphenol + 4-bromo-2-hydroxyphenol + 2 NADP+ + CO2 + 4 H2O
show the reaction diagram
3-bromo-4-hydroxybenzoate + NADPH + bromide + O2 + H+
2,4-dibromophenol + NADP+ + CO2 + 2 H2O
show the reaction diagram
4-hydroxybenzoate + 2 NADPH + 2 bromide + 2 O2 + 2 H+
2,4-dibromophenol + 2 NADP+ + CO2 + 4 H2O
show the reaction diagram
4-hydroxybenzoate + 2 NADPH + 2 iodide + 2 O2 + 2 H+
2,4-diiodophenol + 2 NADP+ + CO2 + 4 H2O
show the reaction diagram
4-hydroxybenzoate + NADPH + bromide + O2 + H+
3-bromo-4-hydroxybenzoate + NADP+ + 2 H2O
show the reaction diagram
additional information
?
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