1.14.15.37: luteothin monooxygenase
This is an abbreviated version!
For detailed information about luteothin monooxygenase, go to the full flat file.
Reaction
+ + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ = + 2 H2O + 2 oxidized ferredoxin [iron-sulfur] cluster
Synonyms
AurH, More, multifunctional cytochrome P450 monooxygenase, NorH
ECTree
Advanced search results
General Information
General Information on EC 1.14.15.37 - luteothin monooxygenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
physiological function
AurH is a unique cytochrome P450 monooxygenase catalyzing the stepwise formation of a homochiral oxygen heterocycle, a key structural and pharmacophoric component of the antibiotic aureothin
physiological function
knockout of AurH in the aureothin biosynthesis gene cluster leads to accumulation of luteothin. AurH catalyzes the formation of the homochiral furan ring of aureothin, which constitutes the last step in the biosynthetic pathway