1.14.14.55: quinine 3-monooxygenase
This is an abbreviated version!
For detailed information about quinine 3-monooxygenase, go to the full flat file.
Word Map on EC 1.14.14.55
-
1.14.14.55
-
cyp2d6
-
cyp1a2
-
drug-drug
-
hepatocytes
-
midazolam
-
ketoconazole
-
p-glycoprotein
-
dosing
-
xenobiotics
-
drug-metabolizing
-
concentration-time
-
clopidogrel
-
testosterone
-
disposition
-
interindividual
-
pharmacodynamics
-
pharmacogenetic
-
pregnane
-
omeprazole
-
coadministration
-
rifampicin
-
antiplatelet
-
erythromycin
-
open-label
-
dextromethorphan
-
phenobarbital
-
tacrolimus
-
ritonavir
-
coadministered
-
n-demethylation
-
itraconazole
-
grapefruit
-
tolbutamide
-
quinidine
-
first-pass
-
warfarin
-
carbamazepine
-
androstane
-
phenytoin
-
clarithromycin
-
voriconazole
-
pharmacogenomics
-
methadone
-
p450-mediated
-
infinity
-
ugt2b7
-
efavirenz
-
ugt1a1
-
vkorc1
-
saquinavir
-
medicine
- 1.14.14.55
- cyp2d6
- cyp1a2
-
drug-drug
- hepatocytes
- midazolam
- ketoconazole
- p-glycoprotein
-
dosing
- xenobiotics
-
drug-metabolizing
-
concentration-time
- clopidogrel
- testosterone
-
disposition
-
interindividual
-
pharmacodynamics
-
pharmacogenetic
-
pregnane
- omeprazole
-
coadministration
- rifampicin
-
antiplatelet
- erythromycin
-
open-label
- dextromethorphan
- phenobarbital
- tacrolimus
- ritonavir
-
coadministered
-
n-demethylation
- itraconazole
- grapefruit
- tolbutamide
- quinidine
-
first-pass
- warfarin
- carbamazepine
-
androstane
- phenytoin
- clarithromycin
- voriconazole
-
pharmacogenomics
- methadone
-
p450-mediated
-
infinity
- ugt2b7
- efavirenz
- ugt1a1
- vkorc1
- saquinavir
- medicine
Reaction
Synonyms
CYP2C19, CYP3A, CYP3A4, CYPIIIA4, cytochrome P450 isoform, EC 1.14.13.67, NF-25, Nifedipine oxidase, P450-PCN1, quinine 3-hydroxylase, Quinine 3-monooxygenase, quinine monooxygenase
ECTree
1.14.14.55 quinine 3-monooxygenaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 1.14.14.55 - quinine 3-monooxygenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
quinine + [reduced NADPH-hemoprotein reductase] + O2
3-hydroxyquinine + [oxidized NADPH-hemoprotein reductase] + H2O
teniposide + [reduced NADPH-hemoprotein reductase] + O2
teniposide catechol + [oxidized NADPH-hemoprotein reductase] + ?
-
-
-
?
quinine + NADPH + O2
3-hydroxyquinine + NADP+ + H2O
-
quinine is used for treatment of severe forms of Plasmodium falciparum malaria, phenotyping of two different populations, overview
-
-
?
quinine + [reduced NADPH-hemoprotein reductase] + O2
3-hydroxyquinine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
quinine + [reduced NADPH-hemoprotein reductase] + O2
3-hydroxyquinine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
?
quinine + [reduced NADPH-hemoprotein reductase] + O2
3-hydroxyquinine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
quinine + [reduced NADPH-hemoprotein reductase] + O2
3-hydroxyquinine + [oxidized NADPH-hemoprotein reductase] + H2O
-
-
-
-
?
