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1.14.14.167: (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase

This is an abbreviated version!
For detailed information about (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase, go to the full flat file.

Reaction

(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
(13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine
+
[oxidized NADPH-hemoprotein reductase]
+
H2O

Synonyms

1-hydroxy-13-O-acetyl-N-methylcanadine 8-hydroxylase, CYP82X1

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.167 (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase

Systematic Name

Systematic Name on EC 1.14.14.167 - (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase

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SYSTEMATIC NAME
IUBMB Comments
(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating)
This cytochrome P-450 (heme-thiolate) enzyme, characterized from the plant Papaver somniferum (opium poppy), participates in the biosynthesis of the isoquinoline alkaloid noscapine.