1.14.11.79: protein-L-histidine (3S)-3-hydroxylase
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For detailed information about protein-L-histidine (3S)-3-hydroxylase, go to the full flat file.
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Synonyms
C14orf169, MAPJD, MDIG, MINA, MINA53, NO52, NO66, protein histidyl hydroxylase, RIOX1, RIOX2
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Systematic Name
Systematic Name on EC 1.14.11.79 - protein-L-histidine (3S)-3-hydroxylase
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protein-L-histidine,2-oxoglutarate:oxygen oxidoreductase (3S-hydroxylating)
The human enzymes encoded by the RIOX1 and RIOX2 genes catalyse the hydroxylation of L-histidine residues in the 60S ribosomal proteins Rpl8 and L27a, respectively. Both proteins contain JmjC and winged helix domains, and both also catalyse histone L-lysine demethylation activities.