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EC Number
Protein Variants
Commentary
Reference
2.1.1.198
A124L
complete loss of binding affinity, mutation abolishes the side chain-mediating H-bond with SAM
758139
2.1.1.198
D100K
complete loss of binding affinity, mutation abolishes the side chain-mediating H-bond with SAM
758139
2.1.1.198
F144A
binding affinities and entropy are moderately affected
758139
2.1.1.198
Y169A
binding affinity and enthalpy/entropy are very similar to that of the wild-type
758139
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