EC Number |
Protein Variants |
Reference |
---|
1.1.3.7 | A77W/R80C/H91N/L170M/V340A/I500M/F501W |
best performer with substrate (S)-1-(4-methoxyphenyl)-ethanol, with a total 800fold enhancement of activity relative to the parental type |
762586 |
1.1.3.7 | F397Y |
mutant shows improved production of 2,5-furandicarboxylic acid, with 70% yield |
762844 |
1.1.3.7 | F501A |
site-directed mutagenesis, kinetics and redox potential compared to the wild-type enzyme, overview |
699213 |
1.1.3.7 | F501A |
site-directed mutagenesis, the mutant shows reduced activity compared to the wild-type enzyme |
673566 |
1.1.3.7 | F501A |
site-directed mutagenesis, the mutant shows strongly reduced O2 reactivity compared to the wild-type enzyme |
725449 |
1.1.3.7 | F501A |
the AAO preference for (S)-1-(4-fluorophenyl)ethanol is increased threefold when the bulky side chain of Phe501 is removed in the F501A variant, which shows a stereoselectivity S/R ratio of 66:1 for this secondary alcohol |
724757 |
1.1.3.7 | F501H |
mutant shows improved production of 2,5-furandicarboxylic acid, with 97% yield |
762844 |
1.1.3.7 | F501W |
site-directed mutagenesis, the mutant shows a twofold increase in O2 reactivity compared to the wild-type enzyme |
725449 |
1.1.3.7 | F501Y |
site-directed mutagenesis, kinetics and redox potential compared to the wild-type enzyme, overview |
699213 |
1.1.3.7 | F501Y |
site-directed mutagenesis, the mutant shows activity similar to the wild-type enzyme |
673566 |