EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.3.2.34 | more |
RBX2 is specific for UBE2F, which mediates neddylation of the RBX2 partner, cullin 5 |
Homo sapiens |
? |
- |
- |
2.3.2.34 | more |
the enzyme participates in neddylation of DNA-dependent protein kinase catalytic subunit |
Homo sapiens |
? |
- |
- |
2.3.2.34 | more |
UBC12 is specific for RBX1 and mediates neddylation of RBX1-associated cullins 1, 2, 3 and 4 |
Homo sapiens |
? |
- |
- |
2.3.2.34 | [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine |
- |
Mus musculus |
[E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine |
- |
? |
2.3.2.34 | [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine |
- |
Homo sapiens |
[E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine |
- |
? |
2.3.2.34 | [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine |
conjugation of NEDD8 to UBC12 requires the involvement of APP-BP1 and UBA3 |
Homo sapiens |
[E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine |
- |
? |