EC Number   |
General Information |
Reference |
|---|
    2.2.1.1 | malfunction |
enzyme knockdown suppresses HCC cell proliferation by inducing reactive eoxygen species accumulation and reactive oxygen species-associated cell-cycle delay |
737175 |
| 2.2.1.1 | malfunction |
enzyme silencing aggravates the effect of chilling on growth in cucumber seedlings. Cucumber seedlings with enzyme inhibition decrease the mRNA level of FBPase |
757929 |
| 2.2.1.1 | malfunction |
transketolase-deficient Salmonella enterica Typhimurium can grow with glucose, but not ribose, as the sole carbon source |
-, 757197 |
| 2.2.1.1 | metabolism |
the enzyme is fundamental in the non-oxidative branch of the pentose phosphate pathway |
757895 |
| 2.2.1.1 | metabolism |
transketolase is a key enzyme of the pentose phosphate pathway, the Calvin cycle and the ribulose monophosphate cycle |
-, 735856 |
| 2.2.1.1 | physiological function |
after anti-transketolase-like enzyme 1 siRNA treatment in HeLa cells, total transketolase activity is significantly reduced and cell proliferation is remarkably inhibited. In endocervical epithelia cells, total transketolase activity and cell proliferation have no significant differences after siRNA treatment |
699274 |
| 2.2.1.1 | physiological function |
enzyme overexpression relieves the effect of chilling on growth in cucumber seedlings. Cucumber seedlings, which overexpress enzyme, promote the mRNA level of FBPase |
757929 |
| 2.2.1.1 | physiological function |
evaluation of the loss-of-function results of transketolase by microinjection of transketolase double-stranded RNAs into germinal vesicle -stage oocytes, and culture of the oocytes in vitro. Despite the complete and specific knockdown of transketolase expression, germinal vesical breakdown occurred and meiosis was arrested at the metaphase I stage. The arrested oocytes exhibit spindle loss, chromosomal aggregation, and declined maturation promoting factor and mitogen-activated protein kinase activities. Transketolase and its associated pentose phosphate pathway play an important role in the MI-MII transition of the oocytes' meiotic cell cycle, but not in the process of germinal vesical breakdown |
719312 |
| 2.2.1.1 | physiological function |
gene disruption mutant displays a significant decrease in both growth on xylose and xylose-fermenting ability, and enzmye is also required for utilization of glucose. The rate of xylose consumption and ethanol production is slightly impaired in overexpressing strains |
719378 |
| 2.2.1.1 | physiological function |
gene knock out from procyclic Trypanosoma brucei results in loss of transketolase activity ,but no growth phenotype is evident in the null mutants. Metabolite profiling to compare wild type and TKT null mutants reveals substantial increases in transketolase substrate metabolites coupled to loss of sedoheptulose 7-phosphate |
720405 |
