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EC Number	General Information	Commentary	Reference
2.1.1.148	physiological function	DNA replication speed in bacteria and archaea that contain the low-activity ThyX enzyme is up to 10fold decreased compared with species that contain the catalytically more efficient ThyA, EC 2.1.1.45. Both ThyX and ThyA participate in frequent reciprocal gene replacement events. The bacterial metabolism continues to modulate the size and composition of prokaryotic genomes. The increased kinetic efficiency of thymidylate synthesis may have contributed to extending the prokaryotic evolutionary potential	700990

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Release 2023.1 (January 2023)