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EC Number
BRENDA No.
Title
Journal
Volume
Pages
Year
Organism
PubMed ID
2.3.2.34
756876
A new NEDD8-ligating system for cullin-4A
Genes Dev.
12
2263-2268
1998
Homo sapiens
9694792
2.3.2.34
757786
A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8
Nat. Struct. Mol. Biol.
11
927-935
2004
Homo sapiens
15361859
2.3.2.34
755751
Cullin RING Ligase 5 (CRL-5) neddylation activation and biological functions
Adv. Exp. Med. Biol.
1217
261-283
2020
Homo sapiens
31898233
2.3.2.34
757647
E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
Mol. Cell
33
483-495
2009
Mus musculus
19250909
2.3.2.34
756386
HUWE1-dependent DNA-PKcs neddylation modulates its autophosphorylation in DNA damage response
Cell Death Dis.
11
400
2020
Homo sapiens
32457294
2.3.2.34
757126
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway
J. Biol. Chem.
274
12036-12042
1999
Homo sapiens
10207026
2.3.2.34
756545
Pharmaceutical inhibition of neddylation as promising treatments for various cancers
Curr. Top. Med. Chem.
19
1059-1069
2019
Homo sapiens
30854973
2.3.2.34
746510
Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes
Structure
21
42-53
2013
Homo sapiens
23201271
2.3.2.34
757651
UBE2M is a stress-inducible dual E2 for neddylation and ubiquitylation that promotes targeted degradation of UBE2F
Mol. Cell
70
1008-1024
2018
Homo sapiens
29932898
2.3.2.34
756564
Validation of NEDD8-conjugating enzyme UBC12 as a new therapeutic target in lung cancer
EBioMedicine
45
81-91
2019
Homo sapiens
31208947
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