EC Number   |
Posttranslational Modification |
Reference |
|---|
   1.17.3.2 | flavoprotein |
- |
704453, 706259 |
| 1.17.3.2 | more |
- |
-, 392993, 393001, 393008, 644555, 644565, 644619, 644620, 644621, 644622, 644623, 644624, 644625, 644627, 644628, 644629, 644632, 644633, 644635, 644638, 644639, 644641, 644642, 644644, 644645, 644647, 644648, 644649, 644650, 644651, 644653, 644654, 644655, 644657, 644658 |
| 1.17.3.2 | more |
bovine milk enzyme: conversion from oxidase into dehydrogenase by treatment with dithioerythritol or dihydrolipoic acid |
644646 |
| 1.17.3.2 | more |
liver enzyme is unstable as dehydrogenase and is gradually converted to oxidase |
644580 |
| 1.17.3.2 | more |
oxidase is converted into an irreversible oxidase form by pretreatment with chymotrypsin, papain or subtilisin, but only partially with trypsin |
644646 |
| 1.17.3.2 | more |
reversible conversion of xanthine dehydrogenase to xanthin oxidase can be achieved by modification of Cys535 and Cys992, tryptic proteolysis of xanthine dehydrogenase after Lys551 or pancreatin cleavage after Leu219 and Lys569 results in irreversible transformation to xanthine oxidase |
644564 |
| 1.17.3.2 | more |
the enzyme from animal tissues can be interconverted to xanthine dehydrogenase, EC 1.1.1.204, the liver enzyme exists in vivo mainly in its dehydrogenase form, but can be converted into the oxidase form by storage at -20°C, by treatment with proteolytic enzymes or with organic solvents, or by thiol reagents such as Cu2+, N-ethylmaleimide or 4-hydroxymercuribenzoate, the effect of the thiol reagents can be reversed by thiols such as 1,4-dithioerythritol, in other animal tissues the enzyme exists almost entirely as EC 1.1.3.22 but can be converted into the dehydrogenase form by 1,4-dithioerythritol |
-, 644582, 644640, 644643 |
| 1.17.3.2 | proteolytic modification |
- |
-, 392993, 393001, 393008, 644555, 644564, 644565, 644580, 644582, 644619, 644620, 644621, 644622, 644623, 644624, 644625, 644627, 644628, 644629, 644632, 644633, 644635, 644638, 644639, 644640, 644641, 644642, 644643, 644644, 644645, 644646, 644647, 644648, 644649, 644650, 644651, 644653, 644654, 644655, 644657, 644658 |
