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EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.222medicine the Notch signaling pathway is involved in numerous developmental cascades in mammals, mutations in the pathway have been implicated in a variety of Human diseases, like CADASIL, spondylocostal dysostosis, alagille syndrome, cancer and multiple sclerosis 691961
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.222synthesis use of manic fringe in engineering of a mammalian O-glycosylation pathway in the yeast Saccharomyces cerevisiae for production of O-fucosylated epidermal growth factor domains. In the system, manic fringe facilitates the addition of N-acetylglucosamine to the EGF domain from factor IX but not from factor VII 692530
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