EC Number   |
Natural Substrates |
|---|
    2.3.2.2 | (5-L-glutamyl)-peptide + acceptor + H+ |
- |
| 2.3.2.2 | (5-L-glutamyl)-peptide + acceptor + H+ |
involved in amino acid transport systems, processing of mercapturic acids, and in pathways of metabolism of prostaglandins, estrogens and leukotrienes |
| 2.3.2.2 | (5-L-glutamyl)-peptide + acceptor + H+ |
concurrent reactions: autotranspeptidation with another donor molecule as acceptor, and hydrolase reaction with H2O as acceptor |
| 2.3.2.2 | (5-L-glutamyl)-peptide + an amino acid |
the enzyme plays an important role on the growth of Helicobacter pylori. Higher GGT activity provides an advantage to the growth of Helicobacter pylori in vitro |
| 2.3.2.2 | (5-L-glutamyl)-peptide + an amino acid |
- |
| 2.3.2.2 | 5-D/L-glutamyl-phenylhydrazine + acceptor |
- |
| 2.3.2.2 | a (5-L-glutamyl)-peptide + an amino acid |
- |
| 2.3.2.2 | glutathione + amino acid |
Ggt1 initiates enzymatic breakdown of GSH by cleavage of the gamma-glutamyl bond and release of cysteinylglycine. Second, the thiol group of the released dipeptide reduces ferric to ferrous iron. A combination of kinetic properties of both reactions results in efficient iron reduction over a broad pH range |
| 2.3.2.2 | glutathione + an amino acid |
involved in 5-L-glutamyl cycle of glutathione metabolism |
| 2.3.2.2 | glutathione + an amino acid |
initial step of glutathione degradation |
