EC Number   |
Natural Substrates |
|---|
   3.1.1.7 | acetylcholine + H2O |
- |
| 3.1.1.7 | acetylcholine chloride + H2O |
- |
| 3.1.1.7 | acetylthiocholine + H2O |
- |
| 3.1.1.7 | more |
- |
| 3.1.1.7 | acetylcholine + H2O |
acetylcholine protects cardiomyocytes from prolonged hypoxia through activation of the PI3K/Akt/HIF-1alpha/VEGF pathway and that cardiomyocyte-derived VEGF promotes angiogenesis in a paracrine fashion |
| 3.1.1.7 | more |
acetylcholinesterase is a serine hydrolase that catalyze the hydrolysis of acetylcholine, thus regulating cholinergic neurotransmission |
| 3.1.1.7 | acetylcholine + H2O |
acetylcholinesterase plays in vivo a key role in cholinergic transmission by catalysing the rapid hydrolysis of the neurotransmitter acetylcholine into acetate and choline |
| 3.1.1.7 | more |
AChE is an acetylcholine-hydrolyzing enzyme and is implicated in cognitive functions and probably plays important roles in neurodegenerative disorders, including Alzheimer's disease |
| 3.1.1.7 | more |
brain acetylcholinesterase activity controls systemic cytokine levels through the cholinergic anti-inflammatory pathway, overview |
| 3.1.1.7 | more |
calcium-activated BuchE, EC 3.1.1.8, acts as a major protective mechanism against suicide inhibition of AchE by organophosphates in this non-neuronal tissue, overview |
