EC Number   |
Natural Substrates |
|---|
   3.1.1.7 | more |
pivotal role in the cholinergic system, rapid termination of nerve impulse transmission |
| 3.1.1.7 | more |
calcium-activated BuchE, EC 3.1.1.8, acts as a major protective mechanism against suicide inhibition of AchE by organophosphates in this non-neuronal tissue, overview |
| 3.1.1.7 | more |
the enzyme is involved in the morphogenetic processes of neuronal and non-neuronal tissues |
| 3.1.1.7 | more |
the reactivation of nerve agent-inhibited acetylcholinesterase by oxime is the most important step in the treatment of nerve agent poisoning, overview |
| 3.1.1.7 | more |
acetylcholinesterase is a serine hydrolase that catalyze the hydrolysis of acetylcholine, thus regulating cholinergic neurotransmission |
| 3.1.1.7 | more |
AChE is an acetylcholine-hydrolyzing enzyme and is implicated in cognitive functions and probably plays important roles in neurodegenerative disorders, including Alzheimer's disease |
| 3.1.1.7 | more |
brain acetylcholinesterase activity controls systemic cytokine levels through the cholinergic anti-inflammatory pathway, overview |
| 3.1.1.7 | more |
inhibition of AChE, along with the butyrylcholinesterase, and restoration of acetylcholine is a therapeutic strategy in treatment of Alzheimer's disease and other forms of dementia |
| 3.1.1.7 | more |
presenilin 1, PS1, is required for enzyme activity in the brain, PS1/A246E transgenic mice have altered AChE activity in several regions also vulnerable in Alzheimer pathology, overview |
| 3.1.1.7 | neuropeptides + H2O |
degradation |
