Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Carbachol | 0.01 mM carbachol leads to a significant increase in enzyme activity in SH-SY5Y cells | Mus musculus | |
Carbachol | a 15 min pretreatment of the cells at 37°C with 0.01 mM atropine completely ablates the carbachol-induced increase in enzyme activity | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
batimastat | - |
Mus musculus | |
EDTA | - |
Mus musculus | |
additional information | not inhibited by GM6001 | Mus musculus | |
muscarine | treatment with 0.01 mM muscarine leads to a 20% decrease in enzyme activity in SN-56 cells | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | enzyme anchorage in the membrane is established via the proline rich membrane anchor transmembrane protein | Mus musculus | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetylcholine + H2O | Mus musculus | - |
choline + acetate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
NB-7 cell | - |
Mus musculus | - |
neuronal cell | - |
Mus musculus | - |
SH-SY5Y cell | - |
Mus musculus | - |
SN-56 cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetylcholine + H2O | - |
Mus musculus | choline + acetate | - |
? | |
acetylthiocholine + H2O | - |
Mus musculus | thiocholine + acetate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AChE | - |
Mus musculus |