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Literature summary for 3.1.1.7 extracted from

  • Herkert, N.M.; Thiermann, H.; Worek, F.
    In vitro kinetic interactions of pyridostigmine, physostigmine and soman with erythrocyte and muscle acetylcholinesterase from different species (2011), Toxicol. Lett., 206, 41-46.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
soman pyridostigmine or physostigmine pre-treatment protects a critical level of muscle AChE from inhibition by soman Cavia porcellus
soman pyridostigmine or physostigmine pre-treatment protects a critical level of muscle AChE from inhibition by soman Homo sapiens
soman pyridostigmine or physostigmine pre-treatment protects a critical level of muscle AChE from inhibition by soman Macaca mulatta
soman pyridostigmine or physostigmine pre-treatment protects a critical level of muscle AChE from inhibition by soman Sus scrofa

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-
Homo sapiens
-
-
-
Macaca mulatta
-
-
-
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
Cavia porcellus
-
erythrocyte
-
Homo sapiens
-
erythrocyte
-
Sus scrofa
-
erythrocyte
-
Macaca mulatta
-
intercostal muscle
-
Cavia porcellus
-
intercostal muscle
-
Homo sapiens
-
intercostal muscle
-
Sus scrofa
-
intercostal muscle
-
Macaca mulatta
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetylcholine + H2O
-
Cavia porcellus choline + acetate
-
?
acetylcholine + H2O
-
Homo sapiens choline + acetate
-
?
acetylcholine + H2O
-
Sus scrofa choline + acetate
-
?
acetylcholine + H2O
-
Macaca mulatta choline + acetate
-
?

Synonyms

Synonyms Comment Organism
AChE
-
Cavia porcellus
AChE
-
Homo sapiens
AChE
-
Sus scrofa
AChE
-
Macaca mulatta