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Literature summary for 3.1.1.7 extracted from

  • Saint-Andre, G.; Kliachyna, M.; Kodepelly, S.; Louise-Leriche, L.; Gillon, E.; Renard, P.; Nachon, F.; Baati, R.; Wagner, A.
    Design, synthesis and evaluation of new α-nucleophiles for the hydrolysis of organophosphorus nerve agents: Application to the reactivation of phosphorylated acetylcholinesterase (2011), Tetrahedron, 67, 6352-6361.
No PubMed abstract available

Activating Compound

Activating Compound Comment Organism Structure
HI-6 poisoned AChE reactivator Homo sapiens
pralidoxime poisoned AChE reactivator Homo sapiens
2-hydroxypyridylamidoxime poisoned AChE reactivator Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
VX (nerve agent) pseudo-irreversible inhibition Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetylcholine + H2O
-
Homo sapiens choline + acetate
-
?

Synonyms

Synonyms Comment Organism
AChE
-
Homo sapiens