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Literature summary for 3.1.1.7 extracted from
- Acetylcholinesterase enzyme inhibitory potential of standardized extract of Trigonella foenum graecum L. and its constituents (2010), Phytomedicine, 17, 292-295.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| galanthamine | - |
Bos taurus |  |
| additional information | inhibitory potency of Trigonella foenum graecum crude seed extract, the ethylacetate fractions gives strong AChE inhibition with IC50 of 0.053 mg/ml, and the total alkaloid fraction inhibits with IC50 of 0.0092 mg/ml, overview | Bos taurus | |
| Trigonelline | - |
Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| commercial preparation | - |
Bos taurus | - |
| erythrocyte | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetylthiocholine + H2O | - |
Bos taurus | acetate + thiocholine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| acetyl cholinesterase | - |
Bos taurus |
| AChE | - |
Bos taurus |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.00127 | - |
- |
Bos taurus | galanthamine | |
| 0.233 | - |
- |
Bos taurus | Trigonelline | |
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Release 2023.1 (January 2023)
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