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Literature summary for 3.1.1.7 extracted from

  • Shenouda, J.; Green, P.; Sultatos, L.
    An evaluation of the inhibition of human butyrylcholinesterase and acetylcholinesterase by the organophosphate chlorpyrifos oxon (2009), Toxicol. Appl. Pharmacol., 241, 135-142.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
chlorpyrifos oxon i.e. (O,O-diethyl O-(3,5,6-trichloro-2-pyridyl)) phosphate, an organophosphate Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetylcholine + H2O Homo sapiens
-
acetate + choline
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetylthiocholine + H2O
-
Homo sapiens acetate + thiocholine
-
?
acetylcholine + H2O
-
Homo sapiens acetate + choline
-
?

Synonyms

Synonyms Comment Organism
More the enzyme belongs to the superfamily of alpha/beta-hydrolase fold proteins Homo sapiens
AChE
-
Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
assay at Homo sapiens