Protein Variants | Comment | Organism |
---|---|---|
additional information | A195G/A434G/C882T/A1011G, reduced amount of LH3 in humans with epidermolysis bullosa simplex, only 30% GGT activity in cell lysate, only 40% GGT activity in the culture medium | Homo sapiens |
additional information | MEF+/-, lysyl hydroxylase 3 knock-out mice, only 80% GGT activity in cell lysate, only 5% GGT activity in the culture medium | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O60568 | - |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cell lysate | - |
Mus musculus | - |
cell lysate | - |
Homo sapiens | - |
culture medium | - |
Mus musculus | - |
culture medium | - |
Homo sapiens | - |
embryonic fibroblast cell line | - |
Mus musculus | - |
fibroblast | - |
Homo sapiens | - |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | 67% expression of LH3 in humans with epidermolysis bullosa simplex | down |
Mus musculus | decrease in lysyl hydroxylase 3 in LH3 knock-out mice | down |
General Information | Comment | Organism |
---|---|---|
physiological function | organization of the extracellular matrix and cytoskeleton | Mus musculus |
physiological function | organization of the extracellular matrix and cytoskeleton | Homo sapiens |