Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP-L-fucose + Lewis antigen | Homo sapiens | on the cell surface of hepatocarcinoma cells H7721 | GDP + fucosylated Lewis antigen | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
at least 6 alpha1,3FucT enzymes III-VII and IX, alpha1,3/1,4FucT III is a bifunctional enzyme | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
H-7721 cell | hepatocarcinoma cell, expression levels of alpha1,3FucT enzyme types in descending order: alphaFucT IV, III, VI, VI, VII, and IX | Homo sapiens | - |
hepatoma cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP-L-fucose + Lewis antigen | on the cell surface of hepatocarcinoma cells H7721 | Homo sapiens | GDP + fucosylated Lewis antigen | - |
? | |
GDP-L-fucose + Lewis antigen | the enzyme, especially subtype FucT VI, is responsible for alpha-1,3-fucosylation in the synthesis of Lewis antigens Lex, SLex, and SDLex on the cell surface consist of sialylated or nonsialylated N-acetyllactosamine located on the outer chains of the glycan moieties of glycolipids or the O-linked glycans of glycoproteins, the isozymes prefer sialylated, alphaFucT III, V, VI, and VII, or nonsialylated, alphaFucT IV and IX, N-acetyllactosamine | Homo sapiens | GDP + fucosylated Lewis antigen | - |
? |
Synonyms | Comment | Organism |
---|---|---|
alpha1,3 fucosyltransferase | - |
Homo sapiens |
alpha1,3/1,4FucT III | - |
Homo sapiens |
alpha1,3FucT IV | - |
Homo sapiens |
alpha1,3FucT IX | - |
Homo sapiens |
alpha1,3FucT V | - |
Homo sapiens |
alpha1,3FucT VI | - |
Homo sapiens |
alpha1,3FucT VII | - |
Homo sapiens |
alphaFucT | - |
Homo sapiens |