Activating Compound | Comment | Organism | Structure |
---|---|---|---|
interleukin-13 | upregulation of enzyme expression | Homo sapiens | |
interleukin-4 | synergistic with retinoic acid in activating the core 4 N-acetylglucosaminyltransferase activity | Homo sapiens | |
retinoic acid | upregulation of enzyme expression, synergistic with interleukin-4 in activating the core 4 N-acetylglucosaminyltransferase activity | Homo sapiens | |
Th2 cytokines | upregulation of enzyme expression | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | complete inactivation at 10 mM | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mn2+ | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme is involved in the mucin biosynthesis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epithelium | airway epithelial cell line | Homo sapiens | - |
NCI-H292 cell | airway epithelial cell line | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme is involved in the mucin biosynthesis | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
C2GnT | - |
Homo sapiens |
core 2 beta 1,6 N-acetylglucosaminyltransferase | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Homo sapiens |