Literature summary for 2.3.2.32 extracted from

Megumi, Y.; Miyauchi, Y.; Sakurai, H.; Nobeyama, H.; Lorick, K.; Nakamura, E.; Chiba, T.; Tanaka, K.; Weissman, A.; Kirisako, T.; Ogawa, O.; Iwai, K.
Multiple roles of Rbx1 in the VBC-Cul2 ubiquitin ligase complex (2005), Genes Cells, 10, 679-691 .

Search for more literature for 2.3.2.32

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in 293T cells	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine	Homo sapiens	-	[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine	-	Homo sapiens	[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine	-	?

Synonyms

Synonyms	Comment	Organism
RBX1	-	Homo sapiens

General Information

General Information	Comment	Organism
metabolism	Rbx1 acts as the E3 for cullin NEDDylation	Homo sapiens

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Release 2023.1 (January 2023)