Literature summary for 2.3.1.B44 extracted from

Zegerman, P.; Bannister, A.J.; Kouzarides, T.
The putative tumour suppressor Fus-2 is an N-acetyltransferase (2000), Oncogene, 19, 161-163 .

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	-	Homo sapiens	5737	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q93015	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acetyl-CoA + nuclear import factor Rch1 residues 23-82	-	Homo sapiens	CoA + N-acetyl-nuclear import factor Rch1 residues 23-82	-	?
additional information	Fus-2 can covalently bind acetyl CoA to form a reactive intermediate and N-acetylates peptides with the initial sequence methionine-aspartic acid using a ping-pong mechanism. No substrate: histones	Homo sapiens	?	-	-

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Release 2023.1 (January 2023)