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Literature summary for 2.3.1.296 extracted from

  • Ohno, Y.; Nara, A.; Nakamichi, S.; Kihara, A.
    Molecular mechanism of the ichthyosis pathology of Chanarin-Dorfman syndrome Stimulation of PNPLA1-catalyzed omega-O-acylceramide production by ABHD5 (2018), J. Dermatol. Sci., 92, 245-253 .
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
a linoleate-containing triacyl-sn-glycerol + an ultra-long-chain omega-hydroxyceramide Homo sapiens
-
 a diacyl-sn-glycerol + a linoleate-esterified acylceramide
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293T cell
-
 Homo sapiens
-
HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
a linoleate-containing triacyl-sn-glycerol + an ultra-long-chain omega-hydroxyceramide
-
 Homo sapiens a diacyl-sn-glycerol + a linoleate-esterified acylceramide
-
 ?
additional information ABHD5 promotes enzyme-dependent acylceramide production by retaining triglycerides in the endoplasmic reticulum and presenting them to the enzyme to promote substrate recognition Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
PNPLA1
-
 Homo sapiens