Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD+ + [protein]-N6-acyl-L-lysine | Homo sapiens | - |
nicotinamide + [protein]-L-lysine + 2'-O-acyl-ADP-ribose | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q96EB6 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | - |
Homo sapiens | - |
fetus | - |
Homo sapiens | - |
lung | fetal lung cell | Homo sapiens | - |
MRC-5 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD+ + [protein]-N6-acyl-L-lysine | - |
Homo sapiens | nicotinamide + [protein]-L-lysine + 2'-O-acyl-ADP-ribose | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SIRT1 | - |
Homo sapiens |
sirtuin 1 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | SIRT1 depletion by RNA interference attenuates capsaicin-induced apoptosis in A-549 cancer cells and autophagy in MRC-5 cells | Homo sapiens |