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Literature summary for 2.3.1.26 extracted from

  • Chang, N.Y.; Chan, Y.J.; Ding, S.T.; Lee, Y.H.; HuangFu, W.C.; Liu, I.H.
    Sterol O-acyltransferase 2 contributes to the yolk cholesterol trafficking during zebrafish embryogenesis (2016), PLoS ONE, 11, e0167644 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.26

Cloned(Commentary)

Cloned (Comment) Organism
expression in HEK 293 cell Danio rerio

Inhibitors

Inhibitors Comment Organism Structure
pyripyropene A
-
 Danio rerio

Organism

Organism UniProt Comment Textmining
Danio rerio
-
-
-
Danio rerio B0UYE4 isoform SOAT1
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Danio rerio
-
embryo both isoforms SOAT1 and SOAT2 express in the yolk syncytial layer, hatching gland and developing cardiovascular as well as digestive systems Danio rerio
-
intestine
-
 Danio rerio
-
liver
-
 Danio rerio
-
additional information isoform SOAT1 is ubiquitously expressed Danio rerio
-
testis
-
 Danio rerio
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
oleoyl-CoA + cholesterol
-
 Danio rerio CoA + cholesterol oleate
-
 ?

General Information

General Information Comment Organism
physiological function zebrafish embryos injected with pyripyropene A or morpholino oligo against SOAT2 in the yolk show significantly larger yolk when compared with wild-type embryos. Overexpression of SOAT2 increases the intracellular lipid droplets Danio rerio