Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-Methylhistamine | - |
Homo sapiens | |
histamine | 0.025-0.1 mM | Homo sapiens | |
additional information | not inhibitory: S-adenosyl-L-methionine | Homo sapiens | |
S-adenosylhomocysteine | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Homo sapiens | |
0.0018 | - |
S-adenosyl-L-methionine | - |
Homo sapiens | |
0.0042 | - |
histamine | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | possible role in modulation of histamine mediated reactions in skin | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
S-adenosyl-L-methionine + histamine = S-adenosyl-L-homocysteine + Ntau-methylhistamine | ordered sequential bi bi reaction mechanism with S-adenosylmethionine as the first substrate and histamine as the second substrate, 1-methylhistamine is the first product to leave and S-adenosylhomocysteine the second | Homo sapiens | |
S-adenosyl-L-methionine + histamine = S-adenosyl-L-homocysteine + Ntau-methylhistamine | sequential reaction mechanism | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skin | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | possible role in modulation of histamine mediated reactions in skin | Homo sapiens | ? | - |
? | |
S-adenosyl-L-methionine + histamine | - |
Homo sapiens | S-adenosyl-L-homocysteine + Ntau-methylhistamine | - |
? |