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Literature summary for 2.1.1.72 extracted from

  • Wons, E.; Mruk, I.; Kaczorowski, T.
    Relaxed specificity of prokaryotic DNA methyltransferases results in DNA site-specific modification of RNA/DNA heteroduplexes (2015), J. Appl. Genet., 56, 539-546 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Escherichia coli
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-
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Escherichia coli E1585-68
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Lactococcus cremoris
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Lactococcus cremoris W15
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + DNA duplex carrying the 5'-AAGCUU-3'/3'-TTCGAA-5' target sequence 100% activity Escherichia coli ?
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S-adenosyl-L-methionine + DNA duplex carrying the 5'-AAGCUU-3'/3'-TTCGAA-5' target sequence 100% activity Lactococcus cremoris ?
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S-adenosyl-L-methionine + DNA duplex carrying the 5'-AAGCUU-3'/3'-TTCGAA-5' target sequence 100% activity Lactococcus cremoris W15 ?
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S-adenosyl-L-methionine + DNA duplex carrying the 5'-AAGCUU-3'/3'-TTCGAA-5' target sequence 100% activity Escherichia coli E1585-68 ?
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-
S-adenosyl-L-methionine + RNA/DNA heteroduplex carrying the 5'-AAGCUU-3'/3'-TTCGAA-5' target sequence low activity. Only the DNA strand of the RNA/DNA heteroduplex is methylated Escherichia coli ?
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-
S-adenosyl-L-methionine + RNA/DNA heteroduplex carrying the 5'-AAGCUU-3'/3'-TTCGAA-5' target sequence low activity. Only the DNA strand of the RNA/DNA heteroduplex is methylated Lactococcus cremoris ?
-
-
S-adenosyl-L-methionine + RNA/DNA heteroduplex carrying the 5'-AAGCUU-3'/3'-TTCGAA-5' target sequence low activity. Only the DNA strand of the RNA/DNA heteroduplex is methylated Lactococcus cremoris W15 ?
-
-
S-adenosyl-L-methionine + RNA/DNA heteroduplex carrying the 5'-AAGCUU-3'/3'-TTCGAA-5' target sequence low activity. Only the DNA strand of the RNA/DNA heteroduplex is methylated Escherichia coli E1585-68 ?
-
-

Synonyms

Synonyms Comment Organism
EcoVIII
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Escherichia coli
isospecific DNA MTase
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Escherichia coli
isospecific DNA MTase
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Lactococcus cremoris
M.LlaCI
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Lactococcus cremoris