Literature summary for 2.1.1.5 extracted from

Saande, C.J.; Pritchard, S.K.; Worrall, D.M.; Snavely, S.E.; Nass, C.A.; Neuman, J.C.; Luchtel, R.A.; Dobiszewski, S.; Miller, J.W.; Vailati-Riboni, M.; Loor, J.J.; Schalinske, K.L.
Dietary egg protein prevents hyperhomocysteinemia via upregulation of hepatic betaine-homocysteine S-methyltransferase activity in folate-restricted rats (2019), J. Nutr., 149, 1369-1376 .

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Application

Application	Comment	Organism
nutrition	rats fed a casein-based diet lacking folate exhibit a 53% increase in circulating homocysteine concentrations compared with rats fed a casein-based diet including folate. Serum homocysteine does not differ between rats fed casein-based diet including folate and egg protein-based diet lacking folate. Hepatic BHMT activity is increased by 45% and 40% by the egg protein-based diet and whole egg-based diet compared with the casein-based diets, respectively	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

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Release 2023.1 (January 2023)