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Literature summary for 2.1.1.355 extracted from

  • Thomas, L.R.; Miyashita, H.; Cobb, R.M.; Pierce, S.; Tachibana, M.; Hobeika, E.; Reth, M.; Shinkai, Y.; Oltz, E.M.
    Functional analysis of histone methyltransferase G9a in B and T lymphocytes (2008), J. Immunol., 181, 485-493.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
B-lymphocyte
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Mus musculus
-
T-lymphocyte
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Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + histone H3(K9)
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Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
H3K9 histone methyltransferase
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Mus musculus
H3K9 HMT
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Mus musculus
histone methyltransferase G9a
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Mus musculus

General Information

General Information Comment Organism
malfunction lymphocyte development is unperturbed in G9a-deficient mice, G9a deficiency results in reduced usage of Iglambda L chains and a corresponding inhibition of Iglambda gene assembly in bone marrow precursors Mus musculus