Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | the WbdD protein is tethered to the membrane via a C-terminal region containing amphipathic helices located between residues 601 and 669 | Escherichia coli | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Escherichia coli O9a | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
WbdD | ambiguous | Escherichia coli |
General Information | Comment | Organism |
---|---|---|
malfunction | membrane preparations from a wbdD mutant have severely diminished mannosyltransferase activity in vitro, and no significant amounts of the WbdA protein are targeted to the membrane fraction. Expression of a polypeptide comprising the WbdD C-terminal region is sufficient to restore both proper localization of WbdA and mannosyltransferase activity | Escherichia coli |
physiological function | WbdD controls polymerization reaction in biosynthesis of the O-polysaccharide by coordinating the correct membrane association required for activity of one of the critical mannosyltransferases, WbdA. Identification of regions in the C terminus of WbdD that contribute to the interaction | Escherichia coli |