DELTAD675/DELTAV676 |
tandem deletion variant, about 16% of wild-type activity |
Homo sapiens |
DELTAS678 |
deletion of Ser678 has no effect on cytochrome c reductase activity or Km values for NADPH or cytochrome c |
Homo sapiens |
DELTAV676 |
repositioning of Trp677 by deletion of Val676 decreases cytochrome c reductase activity, to about 6% of wild-type levels |
Homo sapiens |
W677A |
substitution of Trp677 decreases NADPH-dependent cytochrome c reductase activity 25- to 55fold. W677A substitution abolishes the decrease in cytochrome c reductase activity at low pH |
Homo sapiens |
W677G |
substitution of Trp677 decreases NADPH-dependent cytochrome c reductase activity 25- to 55fold. W677G substitution exhibits only a slight decrease in activity at low pH |
Homo sapiens |
W677G/S678X |
W677G/S678X substitution exhibits only a slight decrease in activity at low pH |
Homo sapiens |