Application | Comment | Organism |
---|---|---|
additional information | the CPR activity in different recombinant enzyme preparations is crucial for in vitro CYP3A5-mediated clearance of midazolam. The level of CPR affects both the affinity/binding of midazolam to the CYP enzyme and the velocity of the metabolic reaction | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expressed in microsome from baculovirus-infected insect cells | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
CPR | - |
Homo sapiens |
NADPH-cytochrome P450 reductase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Homo sapiens |