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Literature summary for 1.5.1.7 extracted from

  • Fujioka, M.
    Active-site residues of saccharopine dehydrogenase (NAD+, lysine-forming) from bakers yeast (1981), Biochem. Soc. Trans., 9, 281-282.
    View publication on PubMed
Search for more literature for 1.5.1.7

Inhibitors

Inhibitors Comment Organism Structure
diethyldicarbonate
-
 Saccharomyces cerevisiae
pyridoxal 5'-phosphate reversible inactivation Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O Saccharomyces cerevisiae last step of alpha-aminoadipate pathway for lysine biosynthesis L-lysine + 2-oxoglutarate + NADH
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 baker's yeast
-

Reaction

Reaction Comment Organism Reaction ID
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-lysine + 2-oxoglutarate + NADH + H+ mechanism Saccharomyces cerevisiae
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O last step of alpha-aminoadipate pathway for lysine biosynthesis Saccharomyces cerevisiae L-lysine + 2-oxoglutarate + NADH
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Saccharomyces cerevisiae