Inhibitors | Comment | Organism | Structure |
---|---|---|---|
amino acids | hydrophobic amino acids with 5 or 6 carbon atoms; hydroxylic amino acids | Candida maltosa | |
L-isoleucine | - |
Candida maltosa | |
L-leucine | - |
Candida maltosa | |
L-norleucine | - |
Candida maltosa | |
L-ornithine | - |
Candida maltosa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.23 | - |
NADH | - |
Candida maltosa | |
0.66 | - |
2-oxoglutarate | - |
Candida maltosa | |
1.6 | - |
L-lysine | - |
Candida maltosa |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | 4% of control activity at 1 mM | Candida maltosa | |
Hg2+ | complete inhibition at 1 mM | Candida maltosa | |
Mn2+ | 46% of control activity at 1 mM | Candida maltosa | |
Sn2+ | 11% of control activity at 1 mM | Candida maltosa | |
Zn2+ | 66% of control activity at 1 mM | Candida maltosa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
45000 | - |
gel filtration | Candida maltosa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O | Candida maltosa | involved in lysine biosynthesis | L-lysine + 2-oxoglutarate + NADH | - |
? | |
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O | Candida maltosa | last step of alpha-aminoadipate pathway for lysine biosynthesis | L-lysine + 2-oxoglutarate + NADH | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida maltosa | - |
- |
- |
Candida maltosa L4 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O | i.e. saccharopine | Candida maltosa | L-lysine + 2-oxoglutarate + NADH | - |
r | |
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O | involved in lysine biosynthesis | Candida maltosa | L-lysine + 2-oxoglutarate + NADH | - |
? | |
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O | last step of alpha-aminoadipate pathway for lysine biosynthesis | Candida maltosa | L-lysine + 2-oxoglutarate + NADH | - |
? | |
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O | i.e. saccharopine | Candida maltosa L4 | L-lysine + 2-oxoglutarate + NADH | - |
r |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
L-lysine + 2-oxoglutarate + NADH | Candida maltosa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Candida maltosa |