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Literature summary for 1.4.3.2 extracted from

  • Carone, S.E.I.; Costa, T.R.; Burin, S.M.; Cintra, A.C.O.; Zoccal, K.F.; Bianchini, F.J.; Tucci, L.F.F.; Franco, J.J.; Torqueti, M.R.; Faccioli, L.H.; Albuquerque, S.; Castro, F.A.; Sampaio, S.V.
    A new L-amino acid oxidase from Bothrops jararacussu snake venom Isolation, partial characterization, and assessment of pro-apoptotic and antiprotozoal activities (2017), Int. J. Biol. Macromol., 103, 25-35 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Leu + H2O + O2 Bothrops jararacussu
-
2-oxo-4-methylvaleric acid + NH3 + H2O2
-
?

Organism

Organism UniProt Comment Textmining
Bothrops jararacussu
-
-
-

Purification (Commentary)

Purification (Comment) Organism
benzamidine-Sepharose 4 column chromatography, phenyl-Sepharose 6 column chromatography, and Sephacryl S-100 gel filtration Bothrops jararacussu

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
Bothrops jararacussu
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Leu + H2O + O2
-
Bothrops jararacussu 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
?

Subunits

Subunits Comment Organism
homodimer 2 * 60360, calculated from amino acid sequence Bothrops jararacussu

Synonyms

Synonyms Comment Organism
LAAO-II
-
Bothrops jararacussu

pI Value

Organism Comment pI Value Maximum pI Value
Bothrops jararacussu isoelectric focusing
-
3.9

General Information

General Information Comment Organism
physiological function the enzyme shows a strong antiprotozoal effect against Leishmania amazonensis and Trypanosoma cruzi Bothrops jararacussu