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Literature summary for 1.4.3.2 extracted from

  • Kasai, K.; Hashiguchi, K.; Takahashi, H.; Kasai, A.; Takeda, S.; Nakano, M.; Ishikawa, T.; Nakamura, T.; Miura, T.
    Recombinant production and evaluation of an antibacterial L-amino acid oxidase derived from flounder Platichthys stellatus (2015), Appl. Microbiol. Biotechnol., 99, 6693-6703 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Pichia pastoris strain GS115 Platichthys stellatus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DL-norleucine + H2O + O2 Platichthys stellatus
-
2-oxocaproate + NH3 + H2O2
-
?
L-Arg + H2O + O2 Platichthys stellatus
-
2-oxo-5-guanidinovaleric acid + NH3 + H2O2
-
?
L-Asp + H2O + O2 Platichthys stellatus
-
oxaloacetate + NH3 + H2O2
-
?
L-Glu + H2O + O2 Platichthys stellatus
-
2-oxoglutarate + NH3 + H2O2
-
?
L-His + H2O + O2 Platichthys stellatus
-
2-oxo-4-imidazolepropionic acid + NH3 + H2O2
-
?
L-Ile + H2O + O2 Platichthys stellatus
-
3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
?
L-Leu + H2O + O2 Platichthys stellatus
-
2-oxo-4-methylvaleric acid + NH3 + H2O2
-
?
L-Lys + H2O + O2 Platichthys stellatus
-
6-amino-2-oxo-hexanoic acid + NH3 + H2O2
-
?
L-Met + H2O + O2 Platichthys stellatus
-
4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
?
L-Orn + H2O + O2 Platichthys stellatus
-
2-oxo-5-aminopentanoate + NH3 + H2O2
-
?
L-Phe + H2O + O2 Platichthys stellatus
-
phenylpyruvate + NH3 + H2O2
-
?
L-Trp + H2O + O2 Platichthys stellatus
-
indole-3-pyruvate + NH3 + H2O2
-
?
L-Tyr + H2O + O2 Platichthys stellatus
-
4-hydroxyphenylpyruvate + NH3 + H2O2
-
?

Organism

Organism UniProt Comment Textmining
Platichthys stellatus D2KWB6
-
-

Purification (Commentary)

Purification (Comment) Organism
HiPrep phenyl column chromatography and Ni-NTA agarose column chromatography Platichthys stellatus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DL-norleucine + H2O + O2
-
Platichthys stellatus 2-oxocaproate + NH3 + H2O2
-
?
L-Arg + H2O + O2
-
Platichthys stellatus 2-oxo-5-guanidinovaleric acid + NH3 + H2O2
-
?
L-Asp + H2O + O2
-
Platichthys stellatus oxaloacetate + NH3 + H2O2
-
?
L-Glu + H2O + O2
-
Platichthys stellatus 2-oxoglutarate + NH3 + H2O2
-
?
L-His + H2O + O2
-
Platichthys stellatus 2-oxo-4-imidazolepropionic acid + NH3 + H2O2
-
?
L-Ile + H2O + O2
-
Platichthys stellatus 3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
-
?
L-Leu + H2O + O2
-
Platichthys stellatus 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
?
L-Lys + H2O + O2
-
Platichthys stellatus 6-amino-2-oxo-hexanoic acid + NH3 + H2O2
-
?
L-Met + H2O + O2
-
Platichthys stellatus 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
-
?
L-Orn + H2O + O2
-
Platichthys stellatus 2-oxo-5-aminopentanoate + NH3 + H2O2
-
?
L-Phe + H2O + O2
-
Platichthys stellatus phenylpyruvate + NH3 + H2O2
-
?
L-Trp + H2O + O2
-
Platichthys stellatus indole-3-pyruvate + NH3 + H2O2
-
?
L-Tyr + H2O + O2
-
Platichthys stellatus 4-hydroxyphenylpyruvate + NH3 + H2O2
-
?

Subunits

Subunits Comment Organism
? x * 52000, SDS-PAGE Platichthys stellatus

Synonyms

Synonyms Comment Organism
LAAO1
-
Platichthys stellatus

Cofactor

Cofactor Comment Organism Structure
FAD
-
Platichthys stellatus

General Information

General Information Comment Organism
physiological function the enzyme inhibits the growth of bacteria (Staphylococci, Yersinia sp. Staphylococcus aureus, and Staphylococcus epidermidis) present in mucus Platichthys stellatus