Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | expression of isozymes LOXL1,3,4 during osteoblast differentiation is highly regulated due to their distinct roles in collagen matrix stabilization and subsequent mineralization | ? | - |
? | |
peptidyl-L-lysyl-peptide + O2 + H2O | Mus musculus | initiation of covalent intermolecular cross-linking of collagen by the enzyme action on telopeptidyl lysine and hydroxylysine residues | peptidyl-allysyl-peptide + NH3 + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
4 isozymes, termed LOX-like proteins 1-4, i.e. LOXL1-4 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MC3T3-E1 cell | osteoblastic cell, CRL-2593, expression of LOXL1, 3, and 4, not 2, expression patterns during cell differentiatin and matrix mineralization, 4 weeks, overview | Mus musculus | - |
osteoblast | expression of isozymes during osteoblast differentiation is highly regulated due to their distinct roles in collagen matrix stabilization and subsequent mineralization | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | expression of isozymes LOXL1,3,4 during osteoblast differentiation is highly regulated due to their distinct roles in collagen matrix stabilization and subsequent mineralization | Mus musculus | ? | - |
? | |
peptidyl-L-lysyl-peptide + O2 + H2O | - |
Mus musculus | peptidyl-allysyl-peptide + NH3 + H2O2 | - |
? | |
peptidyl-L-lysyl-peptide + O2 + H2O | initiation of covalent intermolecular cross-linking of collagen by the enzyme action on telopeptidyl lysine and hydroxylysine residues | Mus musculus | peptidyl-allysyl-peptide + NH3 + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LOX | - |
Mus musculus |
lysyl oxidase | - |
Mus musculus |