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Literature summary for 1.4.3.13 extracted from

  • Atsawasuwan, P.; Mochida, Y.; Parisuthiman, D.; Yamauchi, M.
    Expression of lysyl oxidase isoforms in MC3T3-E1 osteoblastic cells (2005), Biochem. Biophys. Res. Commun., 327, 1042-1046.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus expression of isozymes LOXL1,3,4 during osteoblast differentiation is highly regulated due to their distinct roles in collagen matrix stabilization and subsequent mineralization ?
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?
peptidyl-L-lysyl-peptide + O2 + H2O Mus musculus initiation of covalent intermolecular cross-linking of collagen by the enzyme action on telopeptidyl lysine and hydroxylysine residues peptidyl-allysyl-peptide + NH3 + H2O2
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?

Organism

Organism UniProt Comment Textmining
Mus musculus
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4 isozymes, termed LOX-like proteins 1-4, i.e. LOXL1-4
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Source Tissue

Source Tissue Comment Organism Textmining
MC3T3-E1 cell osteoblastic cell, CRL-2593, expression of LOXL1, 3, and 4, not 2, expression patterns during cell differentiatin and matrix mineralization, 4 weeks, overview Mus musculus
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osteoblast expression of isozymes during osteoblast differentiation is highly regulated due to their distinct roles in collagen matrix stabilization and subsequent mineralization Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information expression of isozymes LOXL1,3,4 during osteoblast differentiation is highly regulated due to their distinct roles in collagen matrix stabilization and subsequent mineralization Mus musculus ?
-
?
peptidyl-L-lysyl-peptide + O2 + H2O
-
Mus musculus peptidyl-allysyl-peptide + NH3 + H2O2
-
?
peptidyl-L-lysyl-peptide + O2 + H2O initiation of covalent intermolecular cross-linking of collagen by the enzyme action on telopeptidyl lysine and hydroxylysine residues Mus musculus peptidyl-allysyl-peptide + NH3 + H2O2
-
?

Synonyms

Synonyms Comment Organism
LOX
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Mus musculus
lysyl oxidase
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Mus musculus