Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3,4-dihydroxybenzoate | - |
Bos taurus | |
ascorbic acid | inhibits the purified enzyme in vitro, and the formation of cross-linked collagen | Bos taurus | |
erythorbic acid | stereoisomer of ascorbic acid | Bos taurus | |
glutathione | slight inhibition | Bos taurus | |
additional information | no inhibition by dehydroascorbic acid | Bos taurus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
34000 | - |
x * 34000, SDS-PAGE | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
peptidyl-L-lysyl-peptide + O2 + H2O | Bos taurus | deamination of lysyl and hydroxylysyl residues is part of the pyridinoline biosynthetic pathway, pyridinoline is involved in formation of intracellular and extracellular collagen cross-links responsible for aging of connective tissue | peptidyl-allysyl-peptide + NH3 + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
46.9fold from aorta by DEAE-cellulose ion exchange chromatography and gel filtration | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
aorta | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1.2 | - |
purified enzyme, substrate polylysine | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
peptidyl-L-lysyl-peptide + O2 + H2O | - |
Bos taurus | peptidyl-allysyl-peptide + NH3 + H2O2 | - |
? | |
peptidyl-L-lysyl-peptide + O2 + H2O | deamination of lysyl and hydroxylysyl residues is part of the pyridinoline biosynthetic pathway, pyridinoline is involved in formation of intracellular and extracellular collagen cross-links responsible for aging of connective tissue | Bos taurus | peptidyl-allysyl-peptide + NH3 + H2O2 | - |
? | |
polylysine + O2 + H2O | - |
Bos taurus | allysine + H2O2 + NH3 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 34000, SDS-PAGE | Bos taurus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Bos taurus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.8 | - |
assay at | Bos taurus |