Literature summary for 1.4.3.1 extracted from

Punzo, D.; Errico, F.; Cristino, L.; Sacchi, S.; Keller, S.; Belardo, C.; Luongo, L.; Nuzzo, T.; Imperatore, R.; Florio, E.; De Novellis, V.; Affinito, O.; Migliarini, S.; Maddaloni, G.; Sisalli, M.J.; Pasqualetti, M.; Pollegioni, L.; Maione, S.; Chiariotti, L.; Usiello, A.
Age-related changes in D-aspartate oxidase promoter methylation control extracellular D-aspartate levels and prevent precocious cell death during brain aging (2016), J. Neurosci., 36, 3064-3078 .

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
D-aspartate + H2O + O2	Mus musculus	-	oxaloacetate + NH3 + H2O2	-	?

Organism	UniProt	Comment	Textmining
Mus musculus	Q0E9Q7	-	-

Source Tissue	Comment	Organism	Textmining
brain	-	Mus musculus	-

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-aspartate + H2O + O2	-	Mus musculus	oxaloacetate + NH3 + H2O2	-	?

Synonyms	Comment	Organism
DASPO	-	Mus musculus
DDO	-	Mus musculus

Cofactor	Comment	Organism	Structure
FAD	-	Mus musculus

General Information	Comment	Organism
physiological function	age-related changes in D-aspartate oxidase promoter methylation control extracellular D-aspartate levels and prevent precocious cell death during brain aging. The enzyme expression is critical to regulate the content of the N-methyl-D-aspartate receptor agonist D-aspartate in adulthood	Mus musculus

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Release 2023.1 (January 2023)