KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
5.5 | - |
D-Aspartate | pH not specified in the publication, temperature not specified in the publication | Rattus norvegicus | |
7.5 | - |
D-Aspartate | pH not specified in the publication, temperature not specified in the publication | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-aspartate + H2O + O2 | Mus musculus | - |
oxaloacetate + NH3 + H2O2 | - |
? | |
D-aspartate + H2O + O2 | Rattus norvegicus | - |
oxaloacetate + NH3 + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
thyroid gland | with about 80 units/mg thyroid enzyme activity | Mus musculus | - |
thyroid gland | with about 80 units/mg thyroid enzyme activity | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-aspartate + H2O + O2 | - |
Mus musculus | oxaloacetate + NH3 + H2O2 | - |
? | |
D-aspartate + H2O + O2 | - |
Rattus norvegicus | oxaloacetate + NH3 + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
D-AspO | - |
Mus musculus |
D-AspO | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Mus musculus | |
FAD | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
metabolism | H2O2 is essential for the iodination of the tyrosyl residues to produce mono- and diiodotyrosine that are the precursors for the synthesis of thyroid hormones T3 and T4. interaction of endogenous D-Asp, D-AspO, and D-aspartate racemase in thyroid gland constitutes an additional biochemical pathway for the production of H2O2 and consequently for the synthesis of thyroid hormones, overview | Mus musculus |
metabolism | H2O2 is essential for the iodination of the tyrosyl residues to produce mono- and diiodotyrosine that are the precursors for the synthesis of thyroid hormones T3 and T4. interaction of endogenous D-Asp, D-AspO, and D-aspartate racemase in thyroid gland constitutes an additional biochemical pathway for the production of H2O2 and consequently for the synthesis of thyroid hormones, overview | Rattus norvegicus |