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Literature summary for 1.4.1.1 extracted from

  • Tolxdorff-Neutzling, R.; Klemme, J.H.
    Metabolic role and regulation of L-alanine dehydrogenase in Rhodopseudomonas capsulata (1982), FEMS Microbiol. Lett., 13, 155-159.
No PubMed abstract available
Search for more literature for 1.4.1.1

Activating Compound

Activating Compound Comment Organism Structure
L-Arg activation Rhodobacter capsulatus

Inhibitors

Inhibitors Comment Organism Structure
L-Ala above 15 mM Rhodobacter capsulatus
L-Asp
-
 Rhodobacter capsulatus
L-Cys
-
 Rhodobacter capsulatus
L-Glutamic acid
-
 Rhodobacter capsulatus
L-Ser
-
 Rhodobacter capsulatus
L-Thr
-
 Rhodobacter capsulatus
oxaloacetate
-
 Rhodobacter capsulatus
phosphoenolpyruvate
-
 Rhodobacter capsulatus
pyruvate above 2 mM Rhodobacter capsulatus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.067
-
 NADH
-
 Rhodobacter capsulatus
0.14
-
 NAD+
-
 Rhodobacter capsulatus
0.37
-
 pyruvate
-
 Rhodobacter capsulatus
0.45
-
 L-Ala
-
 Rhodobacter capsulatus
28
-
 NH4+
-
 Rhodobacter capsulatus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Ala + H2O + NAD+ Rhodobacter capsulatus no function in NH4+-assimilation but rather is required to supply the cells with the appropriate quantities of organic carbon when the organism grows at the expense of L-Ala as C-source and N-source pyruvate + NH3 + NADH
-
 ?

Organism

Organism UniProt Comment Textmining
Rhodobacter capsulatus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rhodobacter capsulatus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Ala + H2O + NAD+
-
 Rhodobacter capsulatus pyruvate + NH3 + NADH
-
 r
L-Ala + H2O + NAD+ no function in NH4+-assimilation but rather is required to supply the cells with the appropriate quantities of organic carbon when the organism grows at the expense of L-Ala as C-source and N-source Rhodobacter capsulatus pyruvate + NH3 + NADH
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9
-
 reductive amination Rhodobacter capsulatus
9.8
-
 oxidative deamination Rhodobacter capsulatus

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Rhodobacter capsulatus
NADH
-
 Rhodobacter capsulatus