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Literature summary for 1.4.1.1 extracted from

  • Vancurova, I.; Vancura, A.; Volc, J.; Neuzil, J.; Behal, V.
    A further characterization of alanine dehydrogenase from Streptomyces aureofaciens (1989), J. Basic Microbiol., 29, 185-189.
    View publication on PubMed
Search for more literature for 1.4.1.1

Inhibitors

Inhibitors Comment Organism Structure
HgCl2
-
 Kitasatospora aureofaciens
L-Ala reductive amination of pyruvate Kitasatospora aureofaciens
L-Ser inhibition of aminating activity Kitasatospora aureofaciens
PCMB
-
 Kitasatospora aureofaciens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
198000
-
 analytical ultracentrifugation Kitasatospora aureofaciens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Ala + H2O + NAD+ Kitasatospora aureofaciens physiological role in nitrogen metabolism in Streptomycetes pyruvate + NH3 + NADH
-
 ?

Organism

Organism UniProt Comment Textmining
Kitasatospora aureofaciens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Ala + H2O + 1,N6-etheno-NAD+ 45% of the activity with NAD+ Kitasatospora aureofaciens pyruvate + NH3 + 1,N6-etheno-NADH
-
 ?
L-Ala + H2O + 3-acetylpyridine-NAD+ as active as NAD+ Kitasatospora aureofaciens pyruvate + H2O + 3-acetylpyridine-NADH
-
 ?
L-Ala + H2O + 3-pyridinealdehyde-NAD+ 5.0% of the activity with NAD+ Kitasatospora aureofaciens ?
-
 ?
L-Ala + H2O + deamino-NAD+ 90.2% of the activity with NAD+ Kitasatospora aureofaciens pyruvate + NH3 + deamino-NADH
-
 ?
L-Ala + H2O + NAD+
-
 Kitasatospora aureofaciens pyruvate + NH3 + NADH
-
 r
L-Ala + H2O + NAD+ physiological role in nitrogen metabolism in Streptomycetes Kitasatospora aureofaciens pyruvate + NH3 + NADH
-
 ?
L-Ala + H2O + nicotinamide guanine dinucleotide 59.9% of the activity with NAD+ Kitasatospora aureofaciens ?
-
 ?

Cofactor

Cofactor Comment Organism Structure
1,N6-etheno-NAD+ 45% of the activity with NAD+ Kitasatospora aureofaciens
3-acetylpyridine-NAD+ as active as NAD+ Kitasatospora aureofaciens
3-pyridinealdehyde-NAD+ 5.0% of the activity with NAD+ Kitasatospora aureofaciens
deamino-NAD+ 90.2% of the activity with NAD+ Kitasatospora aureofaciens
NAD+
-
 Kitasatospora aureofaciens
NADH
-
 Kitasatospora aureofaciens
nicotinamide guanine dinucleotide 59.9% of the activity with NAD+ Kitasatospora aureofaciens