Crystallization (Comment) | Organism |
---|---|
the crystal structures of isopenicillin N synthase in complex with L-alpha-aminoadipoyl-L-cysteine (1-(S)-carboxy-2-thiomethyl)ethyl ester and FeII exposed to O2 and unexposed to O2 are determined to 1.4 and 1.8 A resolutions, respectively | Aspergillus nidulans |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Iron | - |
Aspergillus nidulans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-alpha-aminoadipoyl-L-cysteinyl-D-valine + O2 | Aspergillus nidulans | - |
isopenicillin N + 2 H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus nidulans | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
delta-L-alpha-aminoadipoyl-L-cysteine (1-(S)-carboxy-2-thiomethyl)ethyl ester + O2 | substrate analogue | Aspergillus nidulans | ? + H2O | - |
? | |
L-alpha-aminoadipoyl-L-cysteinyl-D-valine + O2 | - |
Aspergillus nidulans | isopenicillin N + 2 H2O | - |
? | |
additional information | iron-mediated conversion of metal-bound thiolate to sulfenate in crystallographic studies | Aspergillus nidulans | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
IPNS | - |
Aspergillus nidulans |
isopenicillin N synthase | - |
Aspergillus nidulans |