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Literature summary for 1.2.7.4 extracted from

  • Fuchs, G.
    CO2 fixation in acetogenic bacteria: variations on a theme (1986), FEMS Microbiol. Rev., 39, 181-213.
No PubMed abstract available

Metals/Ions

Metals/Ions Comment Organism Structure
Iron CO oxidation occurs at Ni- and FeS containing center C, electrons are transferred from cluster C via center B to external electron acceptors Moorella thermoacetica
Iron the alphabeta dimer contains approximately 9-11 mol of iron and 12-14 mol of acid-labile sulfur per mol of dimer Moorella thermoacetica
Iron the alphabeta dimer contains approximately 9-11 mol of iron and 12-14 mol of acid-labile sulfur per mol of dimer Acetobacterium woodii
Nickel the alphabeta dimer contains approximately 2 mol of nickel per mol of dimer Moorella thermoacetica
Nickel the alphabeta dimer contains approximately 2 mol of nickel per mol of dimer Acetobacterium woodii
Zinc the alphabeta dimer contains approximately 1 mol of zinc per mol of dimer Moorella thermoacetica
Zinc the alphabeta dimer contains approximately 1 mol of zinc per mol of dimer Acetobacterium woodii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CO + H2O + electron acceptor Moorella thermoacetica the physiological role of the enzyme in acetyl-CoA synthesis is the reduction of CO2 to a bound CO, the physiological electron acceptor is not known and may be different in different organisms ?
-
?
CO + H2O + electron acceptor Acetobacterium woodii the physiological role of the enzyme in acetyl-CoA synthesis is the reduction of CO2 to a bound CO, the physiological electron acceptor is not known and may be different in different organisms ?
-
?

Organism

Organism UniProt Comment Textmining
Acetobacterium woodii
-
-
-
Clostridium pasteurianum
-
-
-
Moorella thermoacetica
-
-
-

Reaction

Reaction Comment Organism Reaction ID
CO + H2O + 2 oxidized ferredoxin = CO2 + 2 reduced ferredoxin + 2 H+ CO may react with OH- rather than with H2O Clostridium pasteurianum

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Moorella thermoacetica
120
-
electron acceptor ferredoxin Moorella thermoacetica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CO + H2O + electron acceptor the physiological role of the enzyme in acetyl-CoA synthesis is the reduction of CO2 to a bound CO, the physiological electron acceptor is not known and may be different in different organisms Moorella thermoacetica ?
-
?
CO + H2O + electron acceptor the physiological role of the enzyme in acetyl-CoA synthesis is the reduction of CO2 to a bound CO, the physiological electron acceptor is not known and may be different in different organisms Acetobacterium woodii ?
-
?
CO + H2O + ferredoxin
-
Moorella thermoacetica CO2 + reduced ferredoxin
-
?
CO + H2O + methyl viologen
-
Moorella thermoacetica CO2 + reduced methyl viologen
-
r
CO + H2O + methyl viologen
-
Clostridium pasteurianum CO2 + reduced methyl viologen
-
?
CO + H2O + methyl viologen
-
Acetobacterium woodii CO2 + reduced methyl viologen
-
r
CO + H2O + methylene blue
-
Moorella thermoacetica CO2 + reduced methylene blue
-
?
CO + H2O + rubredoxin most efficient electron acceptor Moorella thermoacetica CO2 + reduced rubredoxin
-
?