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Literature summary for 1.2.3.3 extracted from

  • Chen, L.; Ge, X.; Dou, Y.; Wang, X.; Patel, J.R.; Xu, P.
    Identification of hydrogen peroxide production related genes in Streptococcus sanguinis and their functional relationship with pyruvate oxidase (2011), Microbiology, 157, 13-20.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pyruvate + phosphate + O2 + H2O Streptococcus sanguinis
-
acetyl phosphate + CO2 + H2O2
-
?
pyruvate + phosphate + O2 + H2O Streptococcus sanguinis SK36
-
acetyl phosphate + CO2 + H2O2
-
?

Organism

Organism UniProt Comment Textmining
Streptococcus sanguinis
-
-
-
Streptococcus sanguinis SK36
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pyruvate + phosphate + O2 + H2O
-
Streptococcus sanguinis acetyl phosphate + CO2 + H2O2
-
?
pyruvate + phosphate + O2 + H2O
-
Streptococcus sanguinis SK36 acetyl phosphate + CO2 + H2O2
-
?

Synonyms

Synonyms Comment Organism
SpxB
-
Streptococcus sanguinis

Cofactor

Cofactor Comment Organism Structure
FAD
-
Streptococcus sanguinis
thiamine diphosphate
-
Streptococcus sanguinis

Expression

Organism Comment Expression
Streptococcus sanguinis the expression of spxB is decreased in the acetate kinase and SpxR (a regulator of spxB) mutants down
Streptococcus sanguinis the expression of spxB is significantly increased in the thiamine pyrophosphokinase mutant up

General Information

General Information Comment Organism
physiological function pyruvate oxidase is involved in hydrogen peroxide production Streptococcus sanguinis