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Literature summary for 1.2.1.88 extracted from

  • Hu, C.A.; Lin, W.W.; Valle, D.
    Cloning characterization, and expression of cDNAs encoding human DELTA1-pyrroline-5-carboxylate dehydrogenase (1996), J. Biol. Chem., 271, 9795-9800.
    View publication on PubMed
Search for more literature for 1.2.1.88

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion matrix Homo sapiens 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
62000
-
 ? * 62000, DNA sequence determination Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-pyrroline-5-carboxylate + NAD+ + H2O Homo sapiens
-
 L-glutamate + NADH
-
 ir

Organism

Organism UniProt Comment Textmining
Homo sapiens P30038
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain northern blot analysis Homo sapiens
-
heart northern blot analysis Homo sapiens
-
kidney northern blot analysis Homo sapiens
-
liver
-
 Homo sapiens
-
placenta northern blot analysis Homo sapiens
-
skeletal muscle northern blot analysis Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-pyrroline-5-carboxylate + NAD+ + H2O
-
 Homo sapiens L-glutamate + NADH
-
 ir
additional information enzyme involved in L-proline catabolism Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
? ? * 62000, DNA sequence determination Homo sapiens

Synonyms

Synonyms Comment Organism
P5CDH
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+ dependent on Homo sapiens